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Critical Role of Human T-Lymphotropic Virus Type 1 Accessory Proteins in Viral Replication and Pathogenesis

• Authors : Albrecht, Björn; Lairmore, Michael D.

• Source: Microbiology and Molecular Biology Reviews ; volume 66, issue 3, page 396-406 ; ISSN 1092-2172 1098-5557

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Many more differentially expressed genes (DEGs) result from VOR treatment and Vpr expression than either condition alone.

• Authors : Catherine A. Lewis; David M. Margolis; Edward P. Browne

Subjects: Cell Biology; Molecular Biology; Biotechnology

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Vpr expression results in an increased fraction cells with T CM -like phenotype (CD45RA - CCR7 + ).

• Authors : Catherine A. Lewis; David M. Margolis; Edward P. Browne

Subjects: Cell Biology; Molecular Biology; Biotechnology

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Vpr p300-binding site and p300 acetyltransferrase activity required for combined effect of Vpr and vorinostat (VOR).

• Authors : Catherine A. Lewis; David M. Margolis; Edward P. Browne

Subjects: Cell Biology; Molecular Biology; Biotechnology

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Viral gene expression within productively infected (GFP + ) cells is increased in the presence of Vpr and vorinostat (VOR).

• Authors : Catherine A. Lewis; David M. Margolis; Edward P. Browne

Subjects: Cell Biology; Molecular Biology; Biotechnology

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Effect of single viral gene revertants on productive infection and viral gene expression.

• Authors : Catherine A. Lewis; David M. Margolis; Edward P. Browne

Subjects: Cell Biology; Molecular Biology; Biotechnology

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Memory subsets.

• Authors : Catherine A. Lewis; David M. Margolis; Edward P. Browne

Subjects: Cell Biology; Molecular Biology; Biotechnology

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Vpr expression in functional mutant viruses.

• Authors : Catherine A. Lewis; David M. Margolis; Edward P. Browne

Subjects: Cell Biology; Molecular Biology; Biotechnology

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Vpr localization within cell compartments does not change following vorinostat treatment.

• Authors : Catherine A. Lewis; David M. Margolis; Edward P. Browne

Subjects: Cell Biology; Molecular Biology; Biotechnology

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Induction of cell cycle arrest and apoptosis/cell death by Vpr.

• Authors : Catherine A. Lewis; David M. Margolis; Edward P. Browne

Subjects: Cell Biology; Molecular Biology; Biotechnology

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