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A Study of ABT-414 in Participants With Newly Diagnosed Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplification (Intellance1)

• Authors : Radiation Therapy Oncology Group

• Source: A Randomized, Placebo Controlled Phase 3 Study of ABT-414 With Concurrent Chemoradiation and Adjuvant Temozolomide in Subjects With Newly Diagnosed Glioblastoma (GBM)

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Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomas (INTELLANCE-2)

• Authors : European Organisation for Research and Treatment of Cancer - EORTC

• Source: INTELLANCE-2: ABT-414 Alone or ABT-414 Plus Temozolomide Versus Lomustine or Temozolomide for Recurrent Glioblastoma: A Randomized Phase 2

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Study Evaluating ABT-414 in Japanese Subjects With Malignant Glioma

• Source: A Non-Randomized, Open-Label, Multi-Center Phase 1/2 Study Evaluating the Safety, Pharmacokinetics and Efficacy of ABT-414 in Japanese Subjects With Malignant Glioma

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Expanded Access to ABT-414

• Source: Expanded Access to ABT-414

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Evaluating the Safety and Pharmacokinetics of ABT-414 for Subjects With Glioblastoma Multiforme

• Source: A Phase 1 Study Evaluating the Safety and Pharmacokinetics of ABT-414 for Subjects With Glioblastoma MultiformeLassman AB, Roberts-Rapp L, Sokolova I, Song M,

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A Study of ABT-414 in Subjects With Solid Tumors

• Source: A Phase 1/2 Study Evaluating the Safety, Pharmacokinetics and Efficacy of ABT-414 in Subjects With Advanced Solid Tumors Likely to Over-Express the Epidermal Growth

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Ocular Side Effects of EGFR-Inhibitor ABT-414 in Recurrent Glioblastoma: A Long-Term Safety Study

• Authors : Raffaele Parrozzani; Giuseppe Lombardi; Edoardo Midena

Subjects: ABT-414; confocal microscopy; cornea

• Source: Frontiers in Oncology, Vol 10 (2020)

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Corneal Toxicity Induced by ABT-414 Therapy for Glioblastoma Multiforme: A Case Report

• Authors : Hamoon Eshraghi; Dimosthenis Mantopoulos; Leejee H. Suh

Subjects: Corneal toxicity; ABT-414; EGFR inhibitor

• Source: Case Reports in Ophthalmology, Vol 9, Iss 3, Pp 479-483 (2018)

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Efficacy of depatuxizumab mafodotin (ABT-414) monotherapy in patients with EGFR-amplified, recurrent glioblastoma: results from a multi-center, international study

• Authors : Martin van den Bent; Hui Gan; Andrew B Lassman

Subjects: Uncategorized; ABT-414; Depatuxizumab mafodotin

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Efficacy of depatuxizumab mafodotin (ABT-414) in preclinical models of head and neck cancer

• Authors : Mani, Lucas; Naveed, Abdullah; McAdoo, Ashtyn ...

• Source: Carcinogenesis ; volume 45, issue 7, page 520-526 ; ISSN 0143-3334 1460-2180

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