Search Results

Proteomic profiling reveals that ESR1 mutations enhance cyclin-dependent kinase signaling

• Authors : De Marchi, Tommaso; Lai, Chun-Fui; Simmons, Georgia M

Subjects: Humans; Female; Cyclin-Dependent Kinases/genetics

• Source: Scientific Reports. 14:1-16

Record details

Reprogramming of endothelial gene expression by tamoxifen inhibits angiogenesis and ERα-negative tumor growth.

• Authors : Fébrissy, Chanaëlle; Adlanmerini, Marine; Pequeux, Christel

Subjects: Angiogenesis; Endothelial cells; Estrogen Receptor ERα

• Source: Theranostics, 14 (1), 249 - 264 (2024-01-01)

Record details

Identification of an Imidazopyridine-based Compound as an Oral Selective Estrogen Receptor Degrader for Breast Cancer Therapy

• Authors : Pan, Mengwu; Solozobova, Valeria; Kuznik, Nane ...

Subjects: MESH: Breast Neoplasms/drug therapy; MESH: Estrogen Antagonists/pharmacology; MESH: Estrogen Receptor alpha/genetics

• Source: ISSN: 2767-9764.

Record details

The influence of microsatellite polymorphisms in sex steroid receptor genes ESR1, ESR2 and AR on sex differences in brain structure.

• Authors : Tan, G.C.; Chu, C.; Lee, Y.T.

Subjects: Adolescent; Adult; Aged

• Source: NeuroImage, vol. 221, pp. 117087

Record details

Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk

• Authors : Kramer, Iris; Hooning, Maartje J; Mavaddat, Nasim

Subjects: Adult; Aged; Asian Continental Ancestry Group

• Source: Kramer , I , Hooning , M J , Mavaddat , N , Hauptmann , M , Keeman , R , Steyerberg , E W , Giardiello , D , Antoniou , A C , Pharoah , P D P , Canisius , S , Abu-Ful , Z , Andrulis , I L ,

Record details

Oestrogen receptor α AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium.

• Authors : Cagnet, S.; Ataca, D.; Sflomos, G.

Subjects: Animals; Cell Proliferation; Endocrine System/metabolism

• Source: Nature communications, vol. 9, no. 1, pp. 4723

Record details

SNAI2 upregulation is associated with an aggressive phenotype in fulvestrant-resistant breast cancer cells and is an indicator of poor response to endocrine therapy in estrogen receptor-positive metastatic breast cancer

• Authors : Alves, Carla Maria Lourenco; Elias, Daniel; Lyng, Maria Bibi

Subjects: Endocrine resistance; Epithelial-mesenchymal transition; Estrogen receptor-positive breast cancer

• Source: Alves , C M L , Elias , D , Lyng , M B , Bak , M & Ditzel , H 2018 , ' SNAI2 upregulation is associated with an aggressive phenotype in fulvestrant-resistant breast cancer cells and is an indicator of

Record details

Chemosensitivity to doxorubicin of ER-positive/HER2-negative breast cancers with high 21-gene recurrence score: A study based on in vitro chemoresponse assay.

• Authors : College of Medicine; Dept. of Surgery; Sung Gwe Ahn

Subjects: Adult; Aged; Antineoplastic Agents/pharmacology

Record details

Bazedoxifene, a selective estrogen receptor modulator, reduces cerebral aneurysm rupture in Ovariectomized rats

• Authors : Maekawa, Hidetsugu; Tada, Yoshiteru; Yagi, Kenji

Subjects: Estrogen; Estrogen receptor; Intracranial aneurysm

• Source: Translational Neuroscience

Record details

Predicting Degree of Benefit From Adjuvant Trastuzumab in NSABP Trial B-31

• Authors : Katherine L. Pogue-Geile; Chungyeul Kim; Jong-Hyeon Jeong

Subjects: Antibodies; Monoclonal; Humanized/therapeutic use

Record details