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Quinolinyl-based multitarget-directed ligands with soluble epoxide hydrolase and fatty acid amide hydrolase inhibitory activities: Synthetic studies and pharmacological evaluations

• Authors : Angelia, Jeannes; Duong, Leah; Yun, Faye

Subjects: Pharmacology and Pharmaceutical Sciences; Biomedical and Clinical Sciences; Medicinal and Biomolecular Chemistry

• Source: Heliyon. 10(11)

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4-Phenyl-thiazole-based dual inhibitors of fatty acid amide hydrolase and soluble epoxide hydrolase do not alleviate orofacial inflammatory pain in female rats

• Authors : Carr, Daniel; Chin, Christopher; Chacon, Tiffany

Subjects: Pharmacology and Pharmaceutical Sciences; Biomedical and Clinical Sciences; Neurosciences

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Fatty Acid Amide Hydrolase (FAAH) Inhibitor Treatment of Cannabis Use Disorder (CUD) (FAAH-I MULTI)

• Authors : Columbia University; Johns Hopkins University; Medical University of South Carolina ...

• Source: A Phase 2B, 8-week, Randomized, Double-Blind, Placebo-Controlled, Parallel Study to Evaluate Efficacy, Safety and Tolerability of the Fatty

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A Trial of the Fatty Acid Amide Hydrolase Inhibitor Palmitoylethanolamide in Bipolar Depression

• Authors : Baszucki Brain Research Fund; Rodrigo Machado-Vieira, MD, PhD, MSc, Professor

• Source: A Randomized Controlled Trial of the Fatty Acid Amide Hydrolase Inhibitor

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Transcriptional regulation of the endocannabinoid system in a rat model of binge-eating behavior reveals a selective modulation of the hypothalamic fatty acid amide hydrolase gene

• Authors : Pucci, M; Di Bonaventura, MVM; Zaplatic, E

Subjects: Medicin och hälsovetenskap

• Source: The International journal of eating disorders. 52(1):51-60

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Exploring the fatty acid amide hydrolase and cyclooxygenase inhibitory properties of novel amide derivatives of ibuprofen

• Authors : Deplano, Alessandro; Karlsson, Jessica, 1987; Svensson, Mona

Subjects: Ibuprofen amides; FAAH inhibition; fatty acid amide hydrolase

• Source: Journal of enzyme inhibition and medicinal chemistry (Print). 35(1):815-823

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Elevated Anandamide, Enhanced Recall of Fear Extinction, and Attenuated Stress Responses Following Inhibition of Fatty Acid Amide Hydrolase: A Randomized, Controlled Experimental Medicine Trial

• Authors : Mayo, Leah; Asratian, Anna; Lindé, Johan

Subjects: Anandamide; Cannabinoid; Fatty acid amide hydrolase

• Source: Biological Psychiatry. 87(6):538-547

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Evaluating Fatty Acid Amide Hydrolase as a Suitable Target for Sleep Promotion in a Transgenic TauP301S Mouse Model of Neurodegeneration.

• Authors : Martin, Shenée C.¹ (AUTHOR); Joyce, Kathryn K.¹ (AUTHOR); Harper, Kathryn M.² (AUTHOR)

• Source: Pharmaceuticals (14248247). Mar2024, Vol. 17 Issue 3, p319. 20p.

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Inhibition of Fatty Acid Amide Hydrolase (FAAH) Regulates NF-kb Pathways Reducing Bleomycin-Induced Chronic Lung Inflammation and Pulmonary Fibrosis.

• Authors : Genovese, Tiziana¹ (AUTHOR) ; Duranti, Andrea² (AUTHOR); Monaco, Francesco³ (AUTHOR)

Subjects: *PULMONARY fibrosis; *LUNGS; *PNEUMONIA

• Source: International Journal of Molecular Sciences. Jun2023, Vol. 24 Issue 12, p10125. 15p.

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Pharmacokinetics, pharmacodynamics and safety studies on URB937, a peripherally restricted fatty acid amide hydrolase inhibitor, in rats

• Authors : Vozella, Valentina; Ahmed, Faizy; Choobchian, Paoula

Subjects: Neurosciences; Development of treatments and therapeutic interventions; 6.1 Pharmaceuticals

• Source: Journal of Pharmacy and Pharmacology. 71(12)

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