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Academic Journal

Optimizing the use of in vitro transcribed SGK1-mRNA as a therapeutic tool to treat female infertility.

  • Authors : Sahu I; Department of Pediatrics I-Pediatric Infectiology and Immunology, Translational Genomics and Gene Therapy, University Hospital Tübingen, Wilhelmstraße 27, Tübingen, 72074, Germany.; Ziphius NV, Rijvisschestraat 120, 9052, Ghent, Belgium.

Subjects: Immediate-Early Proteins*/Immediate-Early Proteins*/Immediate-Early Proteins*/genetics ; Immediate-Early Proteins*/Immediate-Early Proteins*/Immediate-Early Proteins*/metabolism ; Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/genetics

  • Source: BMC research notes [BMC Res Notes] 2025 Jul 23; Vol. 18 (1), pp. 318. Date of Electronic Publication: 2025 Jul 23.Publisher: Biomed Central Country of Publication: England NLM ID: 101462768 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-0500

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Academic Journal

SLC7A1 , SGK1 and HMGB2 are overexpressed in cervical cancer tissues and the miR‑23b‑3p/HMGB2 axis regulates cell migration and invasion.

  • Authors : Valente-Niño GW; Infectious Diseases and Cancer Research Laboratory, Faculty of Biological Chemical Sciences, Autonomous University of Guerrero, Chilpancingo, Guerrero 39087, Mexico.; Jiménez-Wences H

Subjects: MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics ; MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism ; Uterine Cervical Neoplasms*/Uterine Cervical Neoplasms*/Uterine Cervical Neoplasms*/genetics

  • Source: Molecular medicine reports [Mol Med Rep] 2025 Sep; Vol. 32 (3). Date of Electronic Publication: 2025 Jun 27.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Unraveling the Potential of SGK1 in Osteoporosis: From Molecular Mechanisms to Therapeutic Targets.

  • Authors : Yang F; Department of Orthopaedics, Lanzhou University Second Hospital, Lanzhou 730030, China.; The Second Clinical Medical School, Lanzhou University, Lanzhou 730030, China.

Subjects: Osteoporosis*/Osteoporosis*/Osteoporosis*/metabolism ; Osteoporosis*/Osteoporosis*/Osteoporosis*/drug therapy ; Osteoporosis*/Osteoporosis*/Osteoporosis*/enzymology

  • Source: Biomolecules [Biomolecules] 2025 May 08; Vol. 15 (5). Date of Electronic Publication: 2025 May 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

Human cytomegalovirus-IE2 suppresses antigen presentation of macrophage through the IL10/STAT3 signalling pathway in transgenic mouse.

  • Authors : Zhang X; Department of Clinical Laboratory, The Affiliated Hospital of Qingdao University, Qingdao, China.; Wang Q

Subjects: STAT3 Transcription Factor*/STAT3 Transcription Factor*/STAT3 Transcription Factor*/metabolism ; Macrophages*/Macrophages*/Macrophages*/immunology ; Macrophages*/Macrophages*/Macrophages*/metabolism

  • Source: PloS one [PLoS One] 2025 May 05; Vol. 20 (5), pp. e0322334. Date of Electronic Publication: 2025 May 05 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Hsa-miR-7974 Suppresses Epstein-Barr Virus Reactivation by Directly Targeting BZLF1 and BRLF1 .

  • Authors : Li H; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.; Wang H

Subjects: Herpesvirus 4, Human*/Herpesvirus 4, Human*/Herpesvirus 4, Human*/physiology ; Herpesvirus 4, Human*/Herpesvirus 4, Human*/Herpesvirus 4, Human*/genetics ; MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics

  • Source: Viruses [Viruses] 2025 Apr 23; Vol. 17 (5). Date of Electronic Publication: 2025 Apr 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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Academic Journal

Heat shock factor 2 regulates oncogenic gamma-herpesvirus gene expression by remodeling the chromatin at the ORF50 and BZLF1 promoter.

  • Authors : Cutrone L; Faculty of Science and Engineering, Cell Biology, Åbo Akademi University, Turku, Finland.; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.

Subjects: Gene Expression Regulation, Viral* ; Trans-Activators*/Trans-Activators*/Trans-Activators*/genetics ; Trans-Activators*/Trans-Activators*/Trans-Activators*/metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2025 Apr 17; Vol. 21 (4), pp. e1013108. Date of Electronic Publication: 2025 Apr 17 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Human MicroRNAs Attenuate the Expression of Immediate Early Proteins and HCMV Replication during Lytic and Latent Infection in Connection with Enhancement of Phosphorylated RelA/p65 (Serine 536) That Binds to MIEP.

  • Authors : Hong YM; Division of Infectious Disease, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 06273, Korea.; Min SY

Subjects: Immediate-Early Proteins*/Immediate-Early Proteins*/Immediate-Early Proteins*/genetics ; Latent Infection* ; MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2022 Mar 02; Vol. 23 (5). Date of Electronic Publication: 2022 Mar 02.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Esaxerenone Improves Vascular Endothelial Dysfunction by Reducing Serum and Glucocorticoid-Regulated Kinase 1 Activity and Enhancing the Akt Pathway in Type 2 Diabetic Mice.

  • Authors : Taguchi K; Department of Physiology and Morphology, Institute of Medicinal Chemistry, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan.; Furukawa T

Subjects: Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/drug therapy ; Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/physiopathology ; Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/metabolism

  • Source: Biological & pharmaceutical bulletin [Biol Pharm Bull] 2025; Vol. 48 (4), pp. 422-431.Publisher: Pharmaceutical Society of Japan Country of Publication: Japan NLM ID: 9311984 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

SGK1-HDAC4-HMGB1 signaling pathway in the spinal cord dorsal horn participates in diabetic neuropathic pain.

  • Authors : Zhang MB; Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Anesthesiology of Zhejiang Province, Wenzhou Medical University, Wenzhou, Zhejiang, China.

Subjects: Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects ; HMGB1 Protein*/HMGB1 Protein*/HMGB1 Protein*/metabolism ; Immediate-Early Proteins*/Immediate-Early Proteins*/Immediate-Early Proteins*/metabolism

  • Source: Molecular pain [Mol Pain] 2025 Jan-Dec; Vol. 21, pp. 17448069251321143.Publisher: Sage Publications Inc Country of Publication: United States NLM ID: 101242662 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Critical Role for the Human Cytomegalovirus Major Immediate Early Proteins in Recruitment of RNA Polymerase II and H3K27Ac To an Enhancer-Like Element in Ori Lyt

Subjects: Gene Expression Regulation, Viral; 0301 basic medicine; herpesviruses

  • Source: Microbiol SpectrMicrobiology Spectrum, Vol 11, Iss 1 (2023)

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  • 1-10 of  7,383 results for ""Immediate-Early Proteins""