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Academic Journal

Autophagy and inflammasome activation are associated with poor response to FLT3 inhibitors in patients with FLT3-ITD acute myeloid leukemia.

  • Authors : Santos de Macedo BG; Department of Medical Images, Hematology, and Oncology, Ribeirão Preto Medical School, University of São Paulo, 3900 Bandeirantes Avenue, Ribeirão Preto, São Paulo, 14040-900, Brazil.; Albuquerque de Melo M

Subjects: fms-Like Tyrosine Kinase 3*/fms-Like Tyrosine Kinase 3*/fms-Like Tyrosine Kinase 3*/genetics ; fms-Like Tyrosine Kinase 3*/fms-Like Tyrosine Kinase 3*/fms-Like Tyrosine Kinase 3*/metabolism ; fms-Like Tyrosine Kinase 3*/fms-Like Tyrosine Kinase 3*/fms-Like Tyrosine Kinase 3*/antagonists & inhibitors

  • Source: Scientific reports [Sci Rep] 2024 Oct 12; Vol. 14 (1), pp. 23882. Date of Electronic Publication: 2024 Oct 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Integrating holotomography and deep learning for rapid detection of NPM1 mutations in AML.

  • Authors : Kim H; Department of Laboratory Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.; Kim G

Subjects: Nucleophosmin* ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/genetics ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/pathology

  • Source: Scientific reports [Sci Rep] 2024 Oct 10; Vol. 14 (1), pp. 23780. Date of Electronic Publication: 2024 Oct 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

The small inhibitor WM-1119 effectively targets KAT6A-rearranged AML, but not KMT2A-rearranged AML, despite shared KAT6 genetic dependency.

  • Authors : Sheridan M; Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, UK.; Maqbool MA

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/genetics ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/drug therapy ; Myeloid-Lymphoid Leukemia Protein*/Myeloid-Lymphoid Leukemia Protein*/Myeloid-Lymphoid Leukemia Protein*/genetics

  • Source: Journal of hematology & oncology [J Hematol Oncol] 2024 Oct 08; Vol. 17 (1), pp. 91. Date of Electronic Publication: 2024 Oct 08.Publisher: Biomed Central Country of Publication: England NLM ID: 101468937 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-8722

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Academic Journal

Single-cell dissection reveals promotive role of ENO1 in leukemia stem cell self-renewal and chemoresistance in acute myeloid leukemia.

  • Authors : Tian Y; Key Laboratory for Regenerative Medicine of Ministry of Education, Institute of Hematology, Jinan University, Guangzhou, 510632, China.; Department of Hematology, First Affiliated Hospital of Jinan University, Guangzhou, 510632, China.

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/metabolism ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/pathology ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/drug therapy

  • Source: Stem cell research & therapy [Stem Cell Res Ther] 2024 Oct 08; Vol. 15 (1), pp. 347. Date of Electronic Publication: 2024 Oct 08.Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512

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Academic Journal

Efficacy and safety of CAR-T therapy targeting CLL1 in patients with extramedullary diseases of acute myeloid leukemia.

  • Authors : Zhao Y; The First Central Clinical College of Tianjin Medical University, Tianjin, 300380, China.; Bai X

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/therapy ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/pathology ; Immunotherapy, Adoptive*/Immunotherapy, Adoptive*/Immunotherapy, Adoptive*/adverse effects

  • Source: Journal of translational medicine [J Transl Med] 2024 Oct 02; Vol. 22 (1), pp. 888. Date of Electronic Publication: 2024 Oct 02.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Academic Journal

CAR T-cell therapy in acute myeloid leukemia.

  • Authors : Almotiri A; From the Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Shaqra University, Shaqra, Kingdom of Saudi Arabia.

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/therapy ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/immunology ; Receptors, Chimeric Antigen*/Receptors, Chimeric Antigen*/Receptors, Chimeric Antigen*/immunology

  • Source: Saudi medical journal [Saudi Med J] 2024 Oct; Vol. 45 (10), pp. 1007-1019.Publisher: Medical Services Department, Saudi Arabian Armed Forces, Ministry Of Defence And Aviation Country of Publication: Saudi Arabia NLM ID: 7909441

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Academic Journal

Effective Prevention and Treatment of Acute Leukemias in Mice by Activation of Thermogenic Adipose Tissues.

  • Authors : Chen R; Department of Cellular and Genetic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.; Cheng T

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/genetics ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/metabolism ; Disease Models, Animal*

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Oct; Vol. 11 (38), pp. e2402332. Date of Electronic Publication: 2024 Jul 25.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

Landscape of biallelic DNMT3A mutant myeloid neoplasms.

  • Authors : Kawashima N; Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, 9620 Carnegie Ave, Building NE6-312, Cleveland, OH, 44106, USA.; Kubota Y

Subjects: DNA Methyltransferase 3A* ; DNA (Cytosine-5-)-Methyltransferases*/DNA (Cytosine-5-)-Methyltransferases*/DNA (Cytosine-5-)-Methyltransferases*/genetics ; Mutation*

  • Source: Journal of hematology & oncology [J Hematol Oncol] 2024 Sep 27; Vol. 17 (1), pp. 87. Date of Electronic Publication: 2024 Sep 27.Publisher: Biomed Central Country of Publication: England NLM ID: 101468937 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-8722

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Academic Journal

RPS6KA1 is a histone acetylation-related oncoprotein in acute myeloid leukemia which is targeted by afzelin.

  • Authors : Guo X; Department of Hematology, Zhongshan People's Hospital, Zhongshan, 528403, Guangdong, China.; Huang G

Subjects: Histones*/Histones*/Histones*/metabolism ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/metabolism ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/genetics

  • Source: BMC cancer [BMC Cancer] 2024 Sep 27; Vol. 24 (1), pp. 1189. Date of Electronic Publication: 2024 Sep 27.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

NL101 synergizes with the BCL-2 inhibitor venetoclax through PI3K-dependent suppression of c-Myc in acute myeloid leukaemia.

  • Authors : Lu Y; Department of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, China.; Institute of Hematology, Ningbo University, Ningbo, China.

Subjects: Bridged Bicyclo Compounds, Heterocyclic*/Bridged Bicyclo Compounds, Heterocyclic*/Bridged Bicyclo Compounds, Heterocyclic*/pharmacology ; Bridged Bicyclo Compounds, Heterocyclic*/Bridged Bicyclo Compounds, Heterocyclic*/Bridged Bicyclo Compounds, Heterocyclic*/therapeutic use ; Sulfonamides*/Sulfonamides*/Sulfonamides*/pharmacology

  • Source: Journal of translational medicine [J Transl Med] 2024 Sep 27; Vol. 22 (1), pp. 867. Date of Electronic Publication: 2024 Sep 27.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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  • 1-10 of  16,746 results for ""Leukemia, Myeloid""