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Academic Journal

Converting cell death into senescence by PARP1 inhibition improves recovery from acute oxidative injury

Authors : Jamil Nehme; Lina Mesilmany; Marta Varela-Eirin

Subjects: 0301 basic medicine; Poly (ADP-Ribose) Polymerase-1/metabolism; Calcium/metabolism

Source: Nature Aging. 4:771-782

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Academic Journal

Health position paper and redox perspectives - Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases.

Authors : Cuadrado, A.; Cazalla, E.; Bach, A.

Subjects: NF-E2-Related Factor 2/metabolism; NF-E2-Related Factor 2/genetics; NF-E2-Related Factor 2/antagonists & inhibitors

Source: Redox biology, vol. 81, pp. 103569

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Academic Journal

Synergistic effects of oxidative and acid stress on bacterial membranes of Escherichia coli and Staphylococcus simulans

Authors : Min Xie; Eveline H. W. Koch; Cornelis A. van Walree ...

Subjects: Plasma Gases; QH301-705.5; Staphylococcus

Source: Commun BiolCommunications Biology, Vol 7, Iss 1, Pp 1-15 (2024)Communications biology, Vol. 7, no.1, p. 1161 (2024)

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Academic Journal

Pyridoxamine Alleviates Cardiac Fibrosis and Oxidative Stress in Western Diet-Induced Prediabetic Rats

Authors : Sarah D’Haese; Lisa Claes; Eva Jaeken ...

Subjects: Male; Blood Glucose; 0301 basic medicine

Source: Int J Mol Sci

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Academic Journal

Novel in vivo TDP-43 stress reporter models to accelerate drug development in ALS

Authors : Ferro, Febe; Wolf, C. Roland; Henstridge, Christopher

Subjects: Amyotrophic Lateral Sclerosis/metabolism; Animals; Mice

Source: Ferro, F, Wolf, C R, Henstridge, C & Inesta-Vaquera, F 2024, 'Novel in vivo TDP-43 stress reporter models to accelerate drug development

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Academic Journal

Methylglyoxal induces death in human brain neuronal cells (SH-SY5Y), prevented by metformin and dapagliflozin

Authors : Victor-Sami, Samantha; Kamali-Roosta, Ali; Shamsaldeen, Yousif A

Subjects: Benzhydryl Compounds - pharmacology; Neurons - drug effects - metabolism; Metformin

Source: Victor-Sami , S , Kamali-Roosta , A & Shamsaldeen , Y A 2024 , ' Methylglyoxal induces death in human brain neuronal cells (SH-SY5Y), prevented by metformin and dapagliflozin ' , Journal of diabetes

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Academic Journal

Specific Compounds Derived from Traditional Chinese Medicine Ameliorate Lipid-Induced Contractile Dysfunction in Cardiomyocytes

Authors : Wang, Fang; Neumann, Dietbert; Kapsokalyvas, Dimitris

Subjects: adult rat cardiomyocytes; contractile function; endosomal CD36 and GLUT4

Source: Wang , F , Neumann , D , Kapsokalyvas , D , Hoes , M F , Schianchi , F , Glatz , J F C , Nabben , M & Luiken , J J F P 2024 , ' Specific Compounds Derived from Traditional Chinese Medicine Ameliorate

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Academic Journal

The absence of gastrointestinal redox dyshomeostasis in the brain-first rat model of Parkinson’s disease induced by bilateral intrastriatal 6-hydroxydopamine

Authors : Jan Homolak; Mihovil Joja; Gracia Grabaric

Subjects: Brain / drug effects; Male; 0301 basic medicine

Source: Mol Neurobiol

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Academic Journal

Adverse renal effects of NLRP3 inflammasome inhibition by MCC950 in an interventional model of diabetic kidney disease

Authors : Jakob A. Østergaard; Jay C. Jha; Arpeeta Sharma

Subjects: Male; Inflammasomes; Mice, Knockout, ApoE

Source: Clin Sci (Lond)Østergaard, J A, Jha, J C, Sharma, A, Dai, A, Choi, J S Y, De Haan, J B, Cooper, M E & Jandeleit-Dah, K 2022, ' Adverse renal effects of NLRP3

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Academic Journal

Role of hepcidin in oxidative stress and cell death of cultured mouse renal collecting duct cells: protection against iron and sensitization to cadmium

Authors : Rachel P. L. van Swelm; Stephanie Probst; Eleni Roussa

Subjects: Male; 0301 basic medicine; Iron

Source: Arch ToxicolArchives of Toxicology, 95, 8, pp. 2719-2735

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