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Rh(II)/Pd(0) Dual Catalysis: Carbenoid N-H Insertion/Allylation Cascade Reaction to Construct Highly Functionalized and Polysubstituted Pyrrolidines.

• Authors : Tang, Maocheng¹ (AUTHOR) ; Jiao, Xianyan¹ (AUTHOR) ; He, Deping¹ (AUTHOR)

Subjects: *ALLYLATION; *DRUG approval; *PYRROLIDINE

• Source: Molecules. Dec2024, Vol. 29 Issue 24, p5880. 26p.

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Construction of N -Aryl-Substituted Pyrrolidines by Successive Reductive Amination of Diketones via Transfer Hydrogenation.

• Authors : Liao, Jianhua¹ (AUTHOR) ; Tong, Jinghui¹ (AUTHOR) ; Liu, Liang¹ (AUTHOR)

Subjects: *TRANSFER hydrogenation; *AMINATION; *KETONES

• Source: Molecules. Jun2024, Vol. 29 Issue 11, p2565. 10p.

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Some cyano-substituted spiro-linked pyrazolines and pyrrolidines with antimicrobial activity

• Authors : Meshcheryakova, Anna A.; Borisova, Svetlana Vasilievna; Konstantinova, Ekaterina A.

Subjects: spirooxoindoles; isatin; 3-dipolar cycloaddition

• Source: Известия Саратовского университета. Новая серия: Серия Химия. Биология. Экология, Vol 24, Iss 4, Pp 374-379 (2024)

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Biocatalytic Construction of Chiral Pyrrolidines and Indolines via Intramolecular C(sp3)-H Amination.

• Authors : Qin, Zi-Yang; Gao, Shilong; Zou, Yike

• Source: ACS Central Science. 9(12)

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A Convenient Synthesis of CHF2O-Containing Pyrrolidines and Related Compounds — Prospective Building Blocks for Drug Discovery

• Authors : Kostiantyn Levchenko; Ivan Virstiuk; Daria Menshykova

Subjects: fluorine; difluoromethoxy group; azetidine

• Source: SynOpen, Vol 08, Iss 04, Pp 247-258 (2024)

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Regio- and stereochemical stability induced by anomeric and gauche effects in difluorinated pyrrolidines

• Authors : Ana Flávia Candida Silva; Francisco A. Martins; Matheus P. Freitas

Subjects: anomeric effect; fluoropyrrolidine; gauche effect

• Source: Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 1572-1579 (2024)

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Fedratinib combined with ropeginterferon alfa-2b in patients with myelofibrosis (FEDORA): study protocol for a multicentre, open-label, Bayesian phase II trial.

• Authors : McIlroy G; Cancer Research UK Clinical Trials Unit (CRCTU), University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. .; Gaskell C

Subjects: Interferon alpha-2*/Interferon alpha-2*/Interferon alpha-2*/administration & dosage ; Interferon alpha-2*/Interferon alpha-2*/Interferon alpha-2*/therapeutic use ; Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/administration & dosage

• Source: BMC cancer [BMC Cancer] 2025 Jan 10; Vol. 25 (1), pp. 56. Date of Electronic Publication: 2025 Jan 10.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Predictive marker for response to trifluridine/tipiracil plus bevacizumab in metastatic colorectal cancer patients.

• Authors : Takahashi T; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-Cho, Kita-Ku, Okayama, 700-8558, Japan.; Shigeyasu K

Subjects: Bevacizumab*/Bevacizumab*/Bevacizumab*/therapeutic use ; Bevacizumab*/Bevacizumab*/Bevacizumab*/administration & dosage ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/drug therapy

• Source: BMC cancer [BMC Cancer] 2025 Jan 02; Vol. 25 (1), pp. 1. Date of Electronic Publication: 2025 Jan 02.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Synthesis of Fluoroalkylated Pyrrolidines through Neat Reaction of Fluoroalkyl Iodides with N, N‐Diallylamines.

• Authors : Mao, Ting¹ (AUTHOR); Li, Weipiao¹ (AUTHOR); Liu, Xiao‐Xiao¹ (AUTHOR)

• Source: Advanced Synthesis & Catalysis. 9/19/2023, Vol. 365 Issue 18, p3063-3068. 6p.

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The Effects of Pangenotypic Direct-Acting Antiviral Therapy on Lipid Profiles and Insulin Resistance in Chronic Hepatitis C Patients.

• Authors : Ko MY; Division of Gastroenterology and Hepatology, Yuanlin Christian Hospital, Changhua 510012, Taiwan.; Hsu YC

Subjects: Hepatitis C, Chronic*/Hepatitis C, Chronic*/Hepatitis C, Chronic*/drug therapy ; Hepatitis C, Chronic*/Hepatitis C, Chronic*/Hepatitis C, Chronic*/virology ; Insulin Resistance*

• Source: Viruses [Viruses] 2025 Feb 14; Vol. 17 (2). Date of Electronic Publication: 2025 Feb 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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