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Optimizing In Vitro Metacyclogenesis: Strain-Specific Variability in Trypanosoma cruzi Responses to Nutritional and pH Stress.

• Authors : Perdomo, Virginia^1,2 (AUTHOR) ; Boselli, Victoria^2,3 (AUTHOR); Manarin, Romina^1,3 (AUTHOR)

• Source: Parasitologia. Jun2025, Vol. 5 Issue 2, p20. 12p.

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Exploring the mechanisms of action of the antimicrobial peptide CZS-5 against Trypanosoma cruzi epimastigotes: insights from metabolomics and molecular dynamics.

• Authors : Osorio-Méndez JF; Laboratorio de Microbiología y Biología Molecular, Programa de Medicina, Facultad de Ciencias Médicas, Corporación Universitaria Empresarial Alexander von Humboldt, Armenia, Colombia. .; Pardo-Rodriguez D

Subjects: Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/drug effects ; Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/metabolism ; Antimicrobial Peptides*/Antimicrobial Peptides*/Antimicrobial Peptides*/pharmacology

• Source: Parasites & vectors [Parasit Vectors] 2025 Jun 05; Vol. 18 (1), pp. 208. Date of Electronic Publication: 2025 Jun 05.Publisher: BioMed Central Country of Publication: England NLM ID: 101462774 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-3305

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Trypanosoma cruzi eIF4E3- and eIF4E4-containing complexes bind different mRNAs and may sequester inactive mRNAs during nutritional stress.

• Authors : Gabiatti, Bernardo Papini^1,2 (AUTHOR); Freire, Eden Ribeiro¹ (AUTHOR); Ferreira da Costa, Jimena¹ (AUTHOR)

Subjects: *Trypanosoma brucei; *Trypanosoma cruzi; *Messenger RNA

• Source: Nucleic Acids Research. 1/27/2025, Vol. 53 Issue 2, p1-21. 21p.

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Beyond Trypanosoma cruzi : LINE-1 Activation as a Driver of Chronic Inflammation in Chagas Disease.

• Authors : Dias, Marina¹ (AUTHOR); Moraes, Aline^1,2 (AUTHOR); Shiroma, Tatiana^1,3 (AUTHOR)

Subjects: *Type I interferons; *Chagas' disease; *Gene expression

• Source: International Journal of Molecular Sciences. May2025, Vol. 26 Issue 10, p4466. 22p.

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Characterizing the transmission dynamics of Trypanosoma cruzi in Triatoma sanguisuga collected from dog kennels in southern Texas.

• Authors : Hernandez C; Molecular Microbiology Laboratory, Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Madigan R

Subjects: Triatoma*/Triatoma*/Triatoma*/parasitology ; Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/genetics ; Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/isolation & purification

• Source: Parasites & vectors [Parasit Vectors] 2025 Jul 15; Vol. 18 (1), pp. 284. Date of Electronic Publication: 2025 Jul 15.Publisher: BioMed Central Country of Publication: England NLM ID: 101462774 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-3305

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Field evidence of Trypanosoma cruzi infection, diverse host use and invasion of human dwellings by the Chagas disease vector in Florida, USA.

• Authors : Beatty NL; Division of Infectious Diseases and Global Medicine, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, United States of America.; Emerging Pathogens Institute, University of Florida, Gainesville, Florida, United States of America.

Subjects: Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/isolation & purification ; Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/genetics ; Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/physiology

• Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2025 Jul 07; Vol. 19 (7), pp. e0012920. Date of Electronic Publication: 2025 Jul 07 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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Cardiac alterations induced by Trypanosoma cruzi extracellular vesicles and immune complexes.

• Authors : Cornet-Gomez A; Department of Parasitology, Biochemical and Molecular Parasitology Group CTS-183, and Institute of Biotechnology, University of Granada, Granada, Spain.; O'Valle F

Subjects: Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/immunology ; Extracellular Vesicles*/Extracellular Vesicles*/Extracellular Vesicles*/immunology ; Antigen-Antibody Complex*/Antigen-Antibody Complex*/Antigen-Antibody Complex*/immunology

• Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2025 Jul 07; Vol. 19 (7), pp. e0013273. Date of Electronic Publication: 2025 Jul 07 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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Association of antibody and T cell receptor repertoires in Trypanosoma cruzi infected rhesus macaques and host response to infection.

• Authors : Clear RM; Department of Tropical Medicine and Infectious Disease, Celia Scott Weatherhead School of Public Health and Tropical Medicine, Vector-Borne and Infectious Disease Research Center, Tulane University, 1440 Canal St., New Orleans, LA, 70112, USA.; Tu W

Subjects: Macaca mulatta*/Macaca mulatta*/Macaca mulatta*/immunology ; Macaca mulatta*/Macaca mulatta*/Macaca mulatta*/parasitology ; Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/immunology

• Source: Journal of biomedical science [J Biomed Sci] 2025 Jun 18; Vol. 32 (1), pp. 58. Date of Electronic Publication: 2025 Jun 18.Publisher: BioMed Central Country of Publication: England NLM ID: 9421567 Publication Model: Electronic Cited Medium: Internet ISSN: 1423-0127

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Natural infection of Trypanosoma Cruzi in client-owned-dogs from rural Yucatan, Mexico.

• Authors : Calderón-Quintal JA; Laboratorio de Parasitología, Centro de Investigaciones Regionales 'Dr Hideyo Noguchi', Universidad Autónoma de Yucatán, Mérida, México.; Escalante-Talavera MJ

Subjects: Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/genetics ; Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/immunology ; Chagas Disease*/Chagas Disease*/Chagas Disease*/veterinary

• Source: Scientific reports [Sci Rep] 2025 Mar 25; Vol. 15 (1), pp. 10263. Date of Electronic Publication: 2025 Mar 25.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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TropD-detector a CRISPR/LbCas12a-based system for rapid screening of Trypanosoma cruzi in Chagas vectors and reservoirs.

• Authors : Ortiz-Rodríguez LA; Centro de Investigaciones en Enfermedades Tropicales(Cintrop). Escuela de Medicina, Departamento de Ciencias Básicas, Universidad Industrial de Santander, Parque Tecnológico y de Investigaciones Guatiguará Km 2 El Refugio, Piedecuesta, Santander, Colombia.; Cabanzo R

Subjects: Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/genetics ; Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/isolation & purification ; Chagas Disease*/Chagas Disease*/Chagas Disease*/parasitology

• Source: Scientific reports [Sci Rep] 2025 May 31; Vol. 15 (1), pp. 19107. Date of Electronic Publication: 2025 May 31.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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