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The deubiquitinase OTUD3 plays a neuroprotective role by reducing ferroptosis induced by cerebral ischaemia reperfusion via stabilizing PLK1 via deubiquitination.

• Authors : Cheng, Jing¹ (AUTHOR); Tian, Qi¹ (AUTHOR); Lu, Hao‐Ran¹ (AUTHOR)

• Source: Clinical & Translational Medicine. May2025, Vol. 15 Issue 5, p1-25. 25p.

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Astragaloside IV regulates FOXM1 deubiquitination to ameliorate trophoblast damage caused by high glucose.

• Authors : Li, Fan¹ (AUTHOR); Zhao, Xiaofang¹ (AUTHOR)

• Source: Hereditas. 6/13/2025, Vol. 162 Issue 1, p1-12. 12p.

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下调 USP46 通过抑制 NLRP3 去泛素化减轻细胞焦亡 改善肾小管上皮细胞缺氧/复氧损伤.

• Authors : 顾世琦¹ ; 倪海强¹; 彭宣¹

• Source: Organ Transplantation / Qi Guan Yi Zhi. May2025, Vol. 16 Issue 3, p416-424. 9p.

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USP5-induced deubiquitination of P4HB alleviates ER stress-mediated apoptosis in intestinal ischemia/reperfusion

• Authors : Shili Ning; Peiyan Zhong; Xuzi Zhao

Subjects: Ischemia/reperfusion; P4HB; ER-stress

• Source: Cellular and Molecular Life Sciences, Vol 82, Iss 1, Pp 1-11 (2025)

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SPICE1 promotes osteosarcoma growth by enhancing the deubiquitination of FASN mediated by USP10.

• Authors : Tong, Weilai^1,2,3 (AUTHOR); Xie, Xinsheng^2,4 (AUTHOR); Shu, Zhiguo^1,2 (AUTHOR)

• Source: Journal of Translational Medicine. 2/21/2025, Vol. 23 Issue 1, p1-16. 16p.

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HOXA5 Derives the Malignant Progression and Cisplatin Resistance of Esophageal Squamous Cell Carcinoma by Regulating USP18‐Mediated IFI27 Deubiquitination.

• Authors : Wang, Qiang¹ (AUTHOR); Ren, Shiheng¹ (AUTHOR); Pan, Zheng² (AUTHOR)

• Source: Thoracic Cancer. Feb2025, Vol. 16 Issue 4, p1-12. 12p.

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Ubiquitin-specific peptidase 14 promotes neuron injury by stabilizing acyl-CoA synthetase long-chain family member 4 through deubiquitination.

• Authors : Hao, Xiaoting^1,2 (AUTHOR); Liu, Ying³ (AUTHOR)

• Source: CytoJournal. 2/6/2025, Vol. 22, p1-9. 9p.

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The Roles of Deubiquitination in Age-related Diseases

• Authors : XU Linhui, LI Pengfei, WU Miaomiao, KANG Lihua, JI Min, YU Ying, GUAN Huaijin

Subjects: aging; age-related diseases; deubiquitination

• Source: Zhongguo quanke yixue, Vol 28, Iss 09, Pp 1143-1155 (2025)

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Insights into the potential role of BMSCs-exo delivered USP14 on SIRT1 deubiquitination in Staphylococcus aureus-induced model of osteomyelitis.

• Authors : Yu, Jun¹; Yang, Ming²; Jin, Yun¹

• Source: Journal of Orthopaedic Surgery & Research. 5/29/2025, Vol. 20 Issue 1, p1-14. 14p.

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NAP1L1 degradation by FBXW7 reduces the deubiquitination of HDGF-p62 signaling to stimulate autophagy and induce primary cisplatin chemosensitivity in nasopharyngeal carcinoma.

• Authors : Gong, Bin^1,2 (AUTHOR); Liu, Yahui¹ (AUTHOR); Yan, Weiwei¹ (AUTHOR)

• Source: Molecular Cancer. 5/26/2025, Vol. 24 Issue 1, p1-30. 30p.

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