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Structural mechanisms of potent lysophosphatidic acid receptor 1 activation by nonlipid basic agonists.

• Authors : Akasaka, Hiroaki¹ (AUTHOR); Sano, Fumiya K.¹ (AUTHOR); Shihoya, Wataru¹ (AUTHOR)

• Source: Communications Biology. 11/6/2024, Vol. 7 Issue 1, p1-9. 9p.

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Lysophosphatidic acid receptor 1 inhibition: a potential treatment target for pulmonary fibrosis.

• Authors : Volkmann, Elizabeth; Denton, Christopher; Kolb, Martin

Subjects: Humans; Receptors; Lysophosphatidic Acid

• Source: European Respiratory Review. 33(172)

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Inhibition of lysophosphatidic acid receptor 1 relieves PMN recruitment in CNS via LPA1/TSP1/CXCR2 pathway and alleviates disruption on blood-brain barrier following intracerebral haemorrhage in mice

• Authors : Ling Gao; Li Peng; Prativa Sherchan

Subjects: Lysophosphatidic acid receptor 1; Intracerebral haemorrhage; AM966

• Source: Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-10 (2023)

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Lysophosphatidic acid receptor 1 (LPAR1) inhibitor compounds

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Lysophosphatidic Acid Receptor 1 Antagonists as Migrastatics for Cancer

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Lysophosphatidic acid receptor 1 inhibition: a potential treatment target for pulmonary fibrosis

• Authors : Volkmann, Elizabeth R; https://orcid.org/0000-0003-3750-6569; Denton, Christopher P

Subjects: Rheumatology Clinic and Institute of Physical Medicine; 610 Medicine & health; Journal Article

• Source: Volkmann, Elizabeth R; Denton, Christopher P; Kolb, Martin; Wijsenbeek-Lourens, Marlies S; Emson, Claire; Hudson, Krischan; Amatucci, Anthony J; Distler, Oliver; Allanore, Yannick; Khanna, Dinesh

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Lysophosphatidic acid receptor 1 inhibition:a potential treatment target for pulmonary fibrosis

• Authors : Volkmann, Elizabeth R.; Denton, Christopher P.; Kolb, Martin

Subjects: article

• Source: Volkmann , E R , Denton , C P , Kolb , M , Wijsenbeek-Lourens , M S , Emson , C , Hudson , K , Amatucci , A J , Distler , O , Allanore , Y & Khanna , D 2024 , '

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Discovery of Chemical Scaffolds as Lysophosphatidic Acid Receptor 1 Antagonists: Virtual Screening, In Vitro Validation, and Molecular Dynamics Analysis

• Authors : Lan Phuong Nguyen; Rasel Ahmed Khan; Soomin Kang

Subjects: Chemistry; QD1-999

• Source: ACS Omega, Vol 8, Iss 43, Pp 40375-40386 (2023)

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Lysophosphatidic acid receptor 1 inhibition: a potential treatment target for pulmonary fibrosis

• Authors : Elizabeth R. Volkmann; Christopher P. Denton; Martin Kolb

Subjects: Diseases of the respiratory system; RC705-779

• Source: European Respiratory Review, Vol 33, Iss 172 (2024)

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Phase 2 trial design of BMS-986278, a lysophosphatidic acid receptor 1 (LPA1) antagonist, in patients with idiopathic pulmonary fibrosis (IPF) or progressive fibrotic interstitial lung disease (PF-ILD)

• Authors : Corte, Tamera J; Lancaster, Lisa; Swigris, Jeffrey J

Subjects: Biomedical and Clinical Sciences; Clinical Sciences; Lung

• Source: BMJ Open Respiratory Research. 8(1)

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