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Micro- and Macroparticle Enhanced Cultivation of Filamentous Lentzea Aerocolonigenes for Increased Rebeccamycin Production

• Authors : Schrinner, Kathrin

Subjects: BiologySCIENCE / Life Sciences / Microbiology

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Morphology engineering for novel antibiotics: Effect of glass microparticles and soy lecithin on rebeccamycin production and cellular morphology of filamentous actinomycete Lentzea aerocolonigenes

• Authors : Anna Dinius; Kathrin Schrinner; Marcel Schrader

Subjects: ddc:660.6; 0301 basic medicine; Morphology Engineering

• Source: Front Bioeng BiotechnolFrontiers in Bioengineering and Biotechnology, Vol 11 (2023)

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The antitumor antibiotic rebeccamycin—challenges and advanced approaches in production processes.

• Authors : Pommerehne, Kathrin^1,2; Walisko, Jana¹; Ebersbach, Anna¹

Subjects: *Rebeccamycin; *Process optimization; *Antineoplastic antibiotics

• Source: Applied Microbiology & Biotechnology. May2019, Vol. 103 Issue 9, p3627-3636. 10p.

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XAD Resins for Increased Rebeccamycin Productivity in Cultivations of Lentzea aerocolonigenes.

• Authors : Schrinner, Kathrin^1,2 (AUTHOR); Althof, Kristina¹ (AUTHOR); Ebersbach, Anna Theresia¹ (AUTHOR)

• Source: Chemie Ingenieur Technik (CIT). Jan2021, Vol. 93 Issue 1/2, p282-288. 7p.

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Macroparticle-enhanced cultivation of Lentzea aerocolonigenes: Variation of mechanical stress and combination with lecithin supplementation for a significantly increased rebeccamycin production

• Authors : Kathrin Schrinner; Marcel Schrader; Jana Niebusch

Subjects: Actinobacteria; 0106 biological sciences; Lecithins

• Source: Biotechnology and Bioengineering. 118:3984-3995

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Transcriptomics and Proteomics Characterizing the Anticancer Mechanisms of Natural Rebeccamycin Analog Loonamycin in Breast Cancer Cells.

• Authors : Sun, Xiao¹ (AUTHOR); Lu, Zhanying¹ (AUTHOR); Liang, Zhenzhen² (AUTHOR)

Subjects: *Triple-negative breast cancer; *Cancer cells; *Breast cancer

• Source: Molecules. Oct2022, Vol. 27 Issue 20, p6958-N.PAG. 15p.

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Rebeccamycin

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Rebeccamycin Analog as Second-Line Therapy in Treating Patients With Limited-Stage or Extensive-Stage Small Cell Lung Cancer That Relapsed After Previous First-Line Chemotherapy

• Source: Phase II Trial of XL119 (Rebeccamycin Analogue) in Relapsed "Sensitive" Small Cell Lung Cancer

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Synthesis of bridged aza-rebeccamycin analogues

• Authors : Messaoudi, S.; Anizon, Fabrice; Pfeiffer, B. ...

Subjects: [CHIM.ORGA]Chemical Sciences/Organic chemistry; 7-Azaindole; Rebeccamycin

• Source: TetrahedronTetrahedron, Elsevier, 2005, pp.7304-7316. ⟨10.1016/j.tet.2005.04.043⟩Tetrahedron, 2005, pp.7304-7316. ⟨10.1016/j.tet.2005.04.043⟩

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Rebeccamycin Analog in Treating Children With Relapsed or Refractory Neuroblastoma

• Authors : National Cancer Institute (NCI)

• Source: A Pharmacokinetic-Guided Phase II Trial of the Rebeccamycin Analog NSC# 655649 in Pediatric Patients With Relapsed/Refractory Neuroblastoma

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