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Short-course Benznidazole Treatment to Reduce Trypanosoma Cruzi Parasitic Load in Women of Reproductive Age (BETTY)

• Authors : Institute for Clinical Effectiveness and Health Policy; University of California, San Diego

• Source: Short-course Benznidazole Treatment to Reduce Trypanosoma Cruzi Parasitic Load in Women of Reproductive Age: A Non-inferiority Randomized Controlled TrialCafferata

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Investigation of the effects of benznidazole on the salivary glands: A biochemical, morphological, and functional approach.

• Authors : Lima-da-Silva, Emanuelly Camilly Soares de¹ (AUTHOR); Melo, Wallacy Watson Pereira¹ (AUTHOR); Mendes, Paulo Fernando Santos¹ (AUTHOR)

Subjects: *Submandibular gland; *Parotid glands; *Rattus norvegicus

• Source: PLoS ONE. 6/3/2025, Vol. 20 Issue 6, p1-17. 17p.

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Pharmacokinetic-pharmacodynamic modeling of benznidazole and its antitrypanosomal activity in a murine model of chronic Chagas disease.

• Authors : Assmus, Frauke^1,2 (AUTHOR); Adehin, Ayorinde^1,2 (AUTHOR); Hoglund, Richard M.^1,2 (AUTHOR)

• Source: PLoS Neglected Tropical Diseases. 5/13/2025, Vol. 19 Issue 5, p1-22. 22p.

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Short Benznidazole Regimen for Chronic Phase Chagas Disease Patients (Benlatino)

• Authors : Andrea Silvestre de Sousa; Israel Molina, Principal Investigator

• Source: Double Blind, Phase III Randomized,Safety and Efficacy Non-inferiority Trial to Evaluate Two Short Benznidazole Regimens for the Treatment of Adults in the Chronic Phase

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Transcriptomic analysis of benznidazole-resistant Trypanosoma cruzi clone reveals nitroreductase I-independent resistance mechanisms.

• Authors : Mejía-Jaramillo, Ana María¹ (AUTHOR) ; Ospina-Zapata, Hader¹ (AUTHOR); Fernandez, Geysson Javier¹ (AUTHOR)

Subjects: *Gene knockout; *Molecular cloning; *Phenotypes

• Source: PLoS ONE. 2/18/2025, Vol. 20 Issue 2, p1-20. 20p.

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Spectroscopic (FT-IR and FT-Raman) and quantum chemical study on monomer and dimer of benznidazole from DFT and molecular docking approaches

• Authors : Tirth Raj Paneru; Manoj Kumar Chaudhary; Poonam Tandon

Subjects: Molecular docking; Benznidazole; Natural bond orbital

• Source: Heliyon, Vol 11, Iss 3, Pp e42104- (2025)

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Anticipating the side effects of benznidazole: HLA-B*35 and patch test

• Authors : Vázquez, Cristina; García-Vázquez, Elisa; Carrilero, Bartolomé ...

Subjects: Male; Adult; Chagas disease

• Source: DIGITUM. Depósito Digital Institucional de la Universidad de MurciaUniversidad de Murcia

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Effects of Free and Nanoencapsulated Benznidazole in Acute Trypanosoma cruzi Infection: Role of Cholinergic Pathway and Redox Status.

• Authors : da Silva, Aniélen D.¹ (AUTHOR) ; Fracasso, Mateus¹ (AUTHOR) ; Bottari, Nathieli B.² (AUTHOR)

• Source: Pharmaceuticals (14248247). Oct2024, Vol. 17 Issue 10, p1397. 30p.

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Repurposing the Antidiabetic Drugs Glyburide, Gliquidone, and Glipizide in Combination with Benznidazole for Trypanosoma cruzi Infection.

• Authors : Vázquez, Citlali¹ (AUTHOR) ; Encalada, Rusely¹ (AUTHOR) ; Jiménez-Galicia, Isabel¹ (AUTHOR)

• Source: Pharmaceuticals (14248247). Jan2025, Vol. 18 Issue 1, p21. 14p.

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Benznidazole-Loaded Polymeric Nanoparticles for Oral Chemotherapeutic Treatment of Chagas Disease.

• Authors : Sousa, Lucas Resende Dutra¹ (AUTHOR) ; Duarte, Thays Helena Chaves² (AUTHOR) ; Xavier, Viviane Flores¹ (AUTHOR)

• Source: Pharmaceutics. Jun2024, Vol. 16 Issue 6, p800. 21p.

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