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Academic Journal

A method for the efficient evaluation of substrate-based cholinesterase imaging probes for Alzheimer's disease.

Authors : Darvesh, Sultan^1,2,3 (AUTHOR) ; Banfield, Scott¹ (AUTHOR); Dufour, Maeve¹ (AUTHOR)

Subjects: *ALZHEIMER'S disease; *ENZYME specificity; *ENZYME kinetics

Source: Journal of Enzyme Inhibition & Medicinal Chemistry. Dec2023, Vol. 38 Issue 1, p1-18. 18p.

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Dysregulated lipid metabolism in TMZ-resistant glioblastoma: pathways, proteins, metabolites and therapeutic opportunities.

Authors : Kao, Tzu-Jen^1,2,3 (AUTHOR); Lin, Chien-Liang⁴ (AUTHOR); Yang, Wen-Bin³ (AUTHOR)

Subjects: *LIPID metabolism; *LIPID synthesis; *GLIOBLASTOMA multiforme

Source: Lipids in Health & Disease. 8/3/2023, Vol. 22 Issue 1, p1-13. 13p.

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Determining minimal clinically important differences in the North Star Ambulatory Assessment (NSAA) for patients with Duchenne muscular dystrophy.

Authors : Ayyar Gupta, Vandana¹ (AUTHOR); Pitchforth, Jacqueline M.¹ (AUTHOR); Domingos, Joana¹ (AUTHOR)

Subjects: *DUCHENNE muscular dystrophy; *PARENT attitudes; *PATIENTS' attitudes

Source: PLoS ONE. 4/26/2023, Vol. 17 Issue 4, p1-17. 17p.

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Fucosylated Human Milk Oligosaccharides during the First 12 Postnatal Weeks Are Associated with Better Executive Functions in Toddlers.

Authors : Willemsen, Yvonne¹ ; Beijers, Roseriet^1,2; Gu, Fangjie³

Subjects: *EXECUTIVE function; *MOTHERS; *BREAST milk

Source: Nutrients. Mar2023, Vol. 15 Issue 6, p1463. 23p.

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Academic Journal

Microglial Cannabinoid CB 2 Receptors in Pain Modulation.

Authors : Xu, Kangtai^1,2 (AUTHOR); Wu, Yifei¹ (AUTHOR); Tian, Zhuangzhuang¹ (AUTHOR)

Subjects: *CANNABINOID receptors; *MICROGLIA; *NOCICEPTORS

Source: International Journal of Molecular Sciences. Feb2023, Vol. 24 Issue 3, p2348. 22p.

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Academic Journal

Therapeutic Effect of Rapamycin on TDP-43-Related Pathogenesis in Ischemic Stroke.

Authors : Tsou, Yi-Syue^1,2,3 (AUTHOR); Lai, Jing-Huei^4,5 (AUTHOR); Chen, Kai-Yun¹ (AUTHOR)

Subjects: *ISCHEMIC stroke; *RAPAMYCIN; *ALZHEIMER'S disease

Source: International Journal of Molecular Sciences. Jan2023, Vol. 24 Issue 1, p676. 18p.

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Inhibition of MZF1/c-MYC Axis by Cantharidin Impairs Cell Proliferation in Glioblastoma.

Authors : Wang, Chie-Hong^1,2,3 (AUTHOR); Wu, Hsuan-Cheng¹ (AUTHOR); Hsu, Chen-Wei¹ (AUTHOR)

Subjects: *CELL proliferation; *ZINC-finger proteins; *CANCER cell proliferation

Source: International Journal of Molecular Sciences. Dec2022, Vol. 23 Issue 23, p14727. 12p.

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Academic Journal

Clinical Trials of New Drugs for Vascular Cognitive Impairment and Vascular Dementia.

Authors : Linh, Tran Thanh Duy^1,2 (AUTHOR); Hsieh, Yi-Chen^3,4,5 (AUTHOR); Huang, Li-Kai^6,7,8 (AUTHOR)

Subjects: *CLINICAL drug trials; *VASCULAR dementia; *COGNITION disorders

Source: International Journal of Molecular Sciences. Oct2022, Vol. 23 Issue 19, p11067. 17p.

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Differences in Immunohistochemical and Ultrastructural Features between Podocytes and Parietal Epithelial Cells (PECs) Are Observed in Developing, Healthy Postnatal, and Pathologically Changed Human Kidneys.

Authors : Ogorevc, Marin¹ (AUTHOR) ; Kosovic, Ivona¹ (AUTHOR) ; Filipovic, Natalija¹ (AUTHOR)

Subjects: *PARIETAL cells; *EPITHELIAL cells; *KIDNEY development

Source: International Journal of Molecular Sciences. Jul2022, Vol. 23 Issue 14, p7501-7501. 22p.

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Effects of transcranial magnetic stimulation over the left posterior superior temporal gyrus on picture-word interference.

Authors : Piai, Vitória^1,2 (AUTHOR) ; Nieberlein, Laura³ (AUTHOR); Hartwigsen, Gesa³ (AUTHOR)

Subjects: *TRANSCRANIAL magnetic stimulation; *SUPERIOR colliculus; *SHEEP

Source: PLoS ONE. 11/30/2020, Vol. 15 Issue 11, p1-18. 18p.

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Structural, Molecular, and Functional Alterations of the Blood-Brain Barrier during Epileptogenesis and Epilepsy: A Cause, Consequence, or Both?

Authors : Löscher, Wolfgang^1,2 ; Friedman, Alon^3,4

Subjects: *BLOOD-brain barrier; *TIGHT junctions; *LEUCOCYTES

Source: International Journal of Molecular Sciences. 1/15/2020, Vol. 21 Issue 2, p1-19. 19p. 3 Diagrams.

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Academic Journal

Adolescent Intermittent Ethanol Increases the Sensitivity to the Reinforcing Properties of Ethanol and the Expression of Select Cholinergic and Dopaminergic Genes within the Posterior Ventral Tegmental Area.

Authors : Hauser, Sheketha R.¹ ; Knight, Christopher P.¹; Truitt, William A.¹

Subjects: *DOPAMINE analysis; *CHOLINERGIC receptors; *ANIMAL behavior

Source: Alcoholism: Clinical & Experimental Research. Sep2019, Vol. 43 Issue 9, p1937-1948. 12p.

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Academic Journal

LatY136F knock-in mouse model for human IgG4-related disease.

Authors : Yamada, Kazunori^1,2; Zuka, Masahiko³; Ito, Kiyoaki¹

Subjects: *IMMUNOGLOBULIN G; *ADAPTOR proteins; *ANTIGEN receptors

Source: PLoS ONE. 6/14/2018, Vol. 13 Issue 6, p1-14. 14p.

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Etiology and functional validation of gastrointestinal motility dysfunction in a zebrafish model of CHARGE syndrome.

Authors : Cloney, Kellie¹; Steele, Shelby L.²; Stoyek, Matthew R.³

Subjects: *GASTROINTESTINAL motility disorders; *CHARGE syndrome; *ZEBRA danio

Source: FEBS Journal. Jun2018, Vol. 285 Issue 11, p2125-2140. 16p.

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Academic Journal

Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study.

Authors : Rosenberry, Terrone L.¹ ; Brazzolotto, Xavier² ; Macdonald, Ian R.³

Subjects: *ACETYLCHOLINESTERASE; *BUTYRYLCHOLINESTERASE; *CRYSTALLOGRAPHY

Source: Molecules. Dec2017, Vol. 22 Issue 12, p2098. 25p. 7 Diagrams, 5 Charts, 3 Graphs.

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Acute Stress and Perceptual Load Consume the Same Attentional Resources: A Behavioral-ERP Study.

Authors : Tiferet-Dweck, Chen^1,2,3 ; Hensel, Michael⁴; Kirschbaum, Clemens⁴

Subjects: *PHYSIOLOGICAL stress; *REACTION time; *ELECTROENCEPHALOGRAPHY

Source: PLoS ONE. 5/19/2016, Vol. 11 Issue 5, p1-19. 19p.

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Academic Journal

Breakdown of Inter-Hemispheric Connectivity Is Associated with Posttraumatic Symptomatology and Memory Impairment.

Authors : Saar-Ashkenazy, Rotem^1,2; Veksler, Ronel³; Guez, Jonathan^4,5

Subjects: *POST-traumatic stress disorder; *MEMORY disorders; *SYMPTOMS

Source: PLoS ONE. 2/10/2016, Vol. 11 Issue 2, p1-14. 14p.

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Academic Journal

Human Nav1.6 Channels Generate Larger Resurgent Currents than Human Nav1.1 Channels, but the Navβ4 Peptide Does Not Protect Either Isoform from Use-Dependent Reduction.

Authors : Patel, Reesha R.^1,2; Barbosa, Cindy³; Xiao, Yucheng^2,3

Subjects: *SODIUM channels; *ACTION potentials; *BRAIN physiology

Source: PLoS ONE. 7/16/2015, Vol. 10 Issue 7, p1-19. 19p.

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Academic Journal

Cranial Nerve Development Requires Co-Ordinated Shh and Canonical Wnt Signaling.

Authors : Kurosaka, Hiroshi^1,2; Trainor, Paul A.^1,3 ; Leroux-Berger, Margot^1,4

Subjects: *CRANIAL nerve diseases; *WNT genes; *CELLULAR signal transduction

Source: PLoS ONE. Mar2015, Vol. 10 Issue 3, p1-19. 19p.

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Academic Journal

A Stem-Cell Based Bioassay to Critically Assess the Pathology of Dysfunctional Neuromuscular Junctions.

Authors : Chipman, Peter H.¹; Zhang, Ying^1,2; Rafuse, Victor F.^1,2,3

Subjects: *NEUROLOGICAL disorders; *BIOLOGICAL assay; *MYONEURAL junction

Source: PLoS ONE. Mar2014, Vol. 9 Issue 3, p1-13. 13p.

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Academic Journal

Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture.

Authors : Koehler, Karl R.¹; Mikosz, Andrew M.²; Molosh, Andrei I.³

Subjects: *EAR; *EPITHELIAL cells; *PLURIPOTENT stem cells

Source: Nature. 8/8/2013, Vol. 500 Issue 7461, p217-221. 5p. 4 Graphs.

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Academic Journal

Brainstem and Cortical Spreading Depolarization in a Closed Head Injury Rat Model.

Authors : Aboghazleh, Refat^1,2 (AUTHOR) ; Parker, Ellen^1,3 (AUTHOR) ; Yang, Lynn T.⁴ (AUTHOR)

Subjects: *ANIMAL disease models; *BRAIN injuries; *HEAD injuries

Source: International Journal of Molecular Sciences. Nov2021, Vol. 22 Issue 21, p11642. 1p.

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Academic Journal

Systemic Bisperoxovanadium Activates Akt/mTOR, Reduces Autophagy, and Enhances Recovery following Cervical Spinal Cord Injury.

Authors : Walker, Chandler L.^1,2; Walker, Melissa J.^2,3; Nai-Kui Liu²

Subjects: *SPINAL cord injuries; *CENTRAL nervous system; *VANADIUM

Source: PLoS ONE. Jan2012, Vol. 7 Issue 1, p1-12. 12p.

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Academic Journal

Sensitization of Ventral Tegmental Area Dopamine Neurons to the Stimulating Effects of Ethanol.

Authors : Zheng-Ming Ding¹ ; Rodd, Zachary A.²; Engleman, Eric A.²

Subjects: *DOPAMINERGIC neurons; *ALCOHOL; *ALCOHOL drinking

Source: Alcoholism: Clinical & Experimental Research. Sep2009, Vol. 33 Issue 9, p1571-1581. 11p. 1 Diagram, 6 Graphs.

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Academic Journal

Stimulating GABAergic Neurons in the Nucleus Accumbens Core Alters the Trigeminal Neuropathic Pain Responses in a Rat Model of Infraorbital Nerve Injury.

Authors : Islam, Jaisan¹ (AUTHOR) ; KC, Elina¹ (AUTHOR) ; Kim, Soochong² (AUTHOR)

Subjects: *GABAERGIC neurons; *NEURALGIA; *NERVOUS system injuries

Source: International Journal of Molecular Sciences. Aug2021, Vol. 22 Issue 16, p8421-8421. 1p.

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Academic Journal

Do Breastfeeding History and Diet Quality Predict Inhibitory Control at Preschool Age?

Authors : Willemsen, Yvonne¹ ; Beijers, Roseriet^1,2 ; Arias Vasquez, Alejandro³

Subjects: *EXECUTIVE function; *STRUCTURAL equation modeling; *NUTRITIONAL assessment

Source: Nutrients. Aug2021, Vol. 13 Issue 8, p2752. 1p.

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Relative Contribution of Proprioceptive and Vestibular Sensory Systems to Locomotion: Opportunities for Discovery in the Age of Molecular Science.

Authors : Akay, Turgay¹ (AUTHOR) ; Murray, Andrew J.² (AUTHOR) ; Jordan, Cynthia L. (AUTHOR)

Subjects: *CENTRAL pattern generators; *SURVIVAL behavior (Animals); *SPINAL cord

Source: International Journal of Molecular Sciences. Feb2021, Vol. 22 Issue 3, p1467-1467. 1p.

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Metabolic Defects Caused by High-Fat Diet Modify Disease Risk through Inflammatory and Amyloidogenic Pathways in a Mouse Model of Alzheimer's Disease.

Authors : Reilly, Austin M.¹ ; Tsai, Andy P.¹ ; Lin, Peter B.¹

Subjects: *ALZHEIMER'S disease; *ANIMAL experimentation; *CELLULAR signal transduction

Source: Nutrients. Oct2020, Vol. 12 Issue 10, p2977. 1p.

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Structural Changes and Astrocyte Response of the Lateral Geniculate Nucleus in a Ferret Model of Ocular Hypertension.

Authors : Fujishiro, Takashi¹ (AUTHOR) ; Honjo, Megumi¹ (AUTHOR) ; Kawasaki, Hiroshi² (AUTHOR)

Subjects: *CONJUNCTIVA; *LATERAL geniculate body; *OCULAR hypertension

Source: International Journal of Molecular Sciences. Feb2020, Vol. 21 Issue 4, p1339. 1p.

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Disrupting hedgehog and WNT signaling interactions promotes cleft lip pathogenesis.

Authors : Hiroshi Kurosaka¹; Iulianella, Angelo²; Williams, Trevor³

Subjects: *CLEFT lip; *HEDGEHOG signaling proteins; *WNT genes

Source: Journal of Clinical Investigation. Apr2014, Vol. 124 Issue 4, p1660-1671. 12p. 7 Color Photographs, 1 Black and White Photograph.

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