Authors : Durães-Oliveira J; Global Health and Tropical Medicine, GHTM, Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, UNL, Rua da Junqueira 100, 1349-008 Lisbon, Portugal.; Palma-Marques J

Subjects: Chagas Disease*/Chagas Disease*/Chagas Disease*/epidemiology ; Chagas Disease*/Chagas Disease*/Chagas Disease*/veterinary ; Trypanosoma cruzi*

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 29; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Spatio-temporal distribution of hospitalizations for chronic Chagas disease and risk factors associated with in-hospital mortality and surgical intervention in Chile.

Authors : Atero N; Escuela de Medicina Veterinaria, Facultad de Agronomía e Ingeniería Forestal, Facultad de Ciencias Biológicas y Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.; Departamento de Salud Pública, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Subjects: Chagas Disease*/Chagas Disease*/Chagas Disease*/mortality ; Chagas Disease*/Chagas Disease*/Chagas Disease*/epidemiology ; Hospitalization*/Hospitalization*/Hospitalization*/statistics & numerical data

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Apr 25; Vol. 18 (4), pp. e0012124. Date of Electronic Publication: 2024 Apr 25 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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Association between environmental gradient of anthropization and phenotypic plasticity in two species of triatomines.

Authors : Fiad FG; Cátedra de Morfología Animal, Facultad de Ciencias Exactas, Físicas y Naturales, Universidad Nacional de Córdoba, Córdoba, Argentina. .; Instituto de Investigaciones Biológicas y Tecnológicas (IIBYT), CONICET, Córdoba, Argentina. .

Subjects: Triatoma*/Triatoma*/Triatoma*/physiology ; Trypanosoma cruzi* ; Chagas Disease*

Source: Parasites & vectors [Parasit Vectors] 2024 Apr 02; Vol. 17 (1), pp. 169. Date of Electronic Publication: 2024 Apr 02.Publisher: BioMed Central Country of Publication: England NLM ID: 101462774 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-3305

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Unmasking the Mechanism behind Miltefosine: Revealing the Disruption of Intracellular Ca 2+ Homeostasis as a Rational Therapeutic Target in Leishmaniasis and Chagas Disease.

Authors : Benaim G; Unidad de Señalización Celular y Bioquímica de Parásitos, Instituto de Estudios Avanzados (IDEA), Caracas 1080, Venezuela.; Laboratorio de Biofísica, Instituto de Biología Experimental, Facultad de Ciencias, Universidad Central de Venezuela, Caracas 1040, Venezuela.

Subjects: Phosphorylcholine*/Phosphorylcholine*/Phosphorylcholine*/*analogs & derivatives; Phosphorylcholine*/Phosphorylcholine*/Phosphorylcholine*/pharmacology ; Phosphorylcholine*/Phosphorylcholine*/Phosphorylcholine*/therapeutic use

Source: Biomolecules [Biomolecules] 2024 Mar 27; Vol. 14 (4). Date of Electronic Publication: 2024 Mar 27.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Synthesis of Antiprotozoal 2-(4-Alkyloxyphenyl)-Imidazolines and Imidazoles and Their Evaluation on Leishmania mexicana and Trypanosoma cruzi .

Authors : Torres-Jaramillo J; Departamento de Química Orgánica, Escuela Nacional de Ciencias Biológicas del Instituto Politécnico Nacional (ENCB-IPN), Mexico City 11340, Mexico.; Blöcher R

Subjects: Imidazolines* ; Trypanosoma cruzi* ; Leishmania mexicana*

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 26; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Comparative evaluation of four rapid diagnostic tests that detect human Trypanosoma cruzi-specific antibodies to support diagnosis of Chagas Disease in urban population of Argentina.

Authors : Rivero R; ANLIS Administración Nacional de Laboratorios y Salud, Instituto Nacional de Parasitología 'Dr. Mario Fatala Chaben', Buenos Aires, Argentina.; CONICET Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.

Subjects: Trypanosoma cruzi* ; Chagas Disease*/Chagas Disease*/Chagas Disease*/diagnosis ; Chagas Disease*/Chagas Disease*/Chagas Disease*/epidemiology

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Mar 15; Vol. 18 (3), pp. e0011997. Date of Electronic Publication: 2024 Mar 15 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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High-throughput analysis of the Trypanosoma cruzi minicirculome (mcDNA) unveils structural variation and functional diversity.

Authors : Gómez-Palacio A; Laboratorio de Investigación en Genética Evolutiva, Universidad Pedagógica y Tecnológica de Colombia, Boyacá, Colombia.; Cruz-Saavedra L

Subjects: Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/genetics ; Chagas Disease* ; Social Segregation*

Source: Scientific reports [Sci Rep] 2024 Mar 07; Vol. 14 (1), pp. 5578. Date of Electronic Publication: 2024 Mar 07.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Validation of Trypanosoma cruzi inactivation techniques for laboratory use.

Authors : MacLean LM; Drug Discovery Unit, Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.; Ariyanayagam M

Subjects: Trypanosoma cruzi* ; Chagas Disease*/Chagas Disease*/Chagas Disease*/parasitology ; Aminopyridines*

Source: PloS one [PLoS One] 2024 Apr 18; Vol. 19 (4), pp. e0300021. Date of Electronic Publication: 2024 Apr 18 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Chemoselective Synthesis and Anti-Kinetoplastidal Properties of 2,6-Diaryl-4 H -tetrahydro-thiopyran-4-one S -Oxides: Their Interplay in a Cascade of Redox Reactions from Diarylideneacetones.

Authors : Gendron T; UMR7042 Université de Strasbourg-CNRS-UHA, Laboratoire d'Innovation Moléculaire et Applications (LIMA), Team Bio(IN)organic and Medicinal Chemistry, European School of Chemistry, Polymers and Materials (ECPM), 25 Rue Becquerel, F-67087 Strasbourg, France.; Lanfranchi DA

Subjects: Chagas Disease* ; Prodrugs* ; Pyrans*

Source: Molecules (Basel, Switzerland) [Molecules] 2024 Apr 04; Vol. 29 (7). Date of Electronic Publication: 2024 Apr 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Comparative proteomic analysis of the hemolymph and salivary glands of Rhodnius prolixus and R. colombiensis reveals candidates associated with differential lytic activity against Trypanosoma cruzi Dm28c and T. cruzi Y.

Authors : Barbosa HJ; Laboratorio de Investigaciones en Parasitología Tropical (LIPT), Facultad de Ciencias, Universidad del Tolima, Ibagué, Colombia.; Quevedo YS

Subjects: Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/genetics ; Rhodnius*/Rhodnius*/Rhodnius*/parasitology ; Chagas Disease*

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Apr 03; Vol. 18 (4), pp. e0011452. Date of Electronic Publication: 2024 Apr 03 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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Integrated Computational Approaches for Drug Design Targeting Cruzipain.

Authors : Parvez A; Department of Electronics and Information Engineering, Jeonbuk National University, Jeonju 54896, Republic of Korea.; Lee JS

Subjects: Cysteine Endopeptidases* ; Chagas Disease*/Chagas Disease*/Chagas Disease*/drug therapy; Humans

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 27; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 27.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Relationship between genetic diversity and morpho-functional characteristics of flight-related traits in Triatoma garciabesi (Hemiptera: Reduviidae).

Authors : Verly T; Centro Nacional de Diagnóstico e Investigación en Endemo-Epidemias (CeNDIE), Administración Nacional de Laboratorios e Institutos de Salud 'Dr. Carlos Malbrán' (ANLIS), Buenos Aires, Argentina.; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.

Subjects: Triatoma* ; Chagas Disease*; Male

Source: Parasites & vectors [Parasit Vectors] 2024 Mar 18; Vol. 17 (1), pp. 145. Date of Electronic Publication: 2024 Mar 18.Publisher: BioMed Central Country of Publication: England NLM ID: 101462774 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-3305

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Small molecule mediators of host-T. cruzi-environment interactions in Chagas disease.

Authors : Kwakye-Nuako G; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma, United States of America.; Department of Biomedical Sciences, School of Allied Health Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.

Subjects: Chagas Disease*/Chagas Disease*/Chagas Disease*/metabolism ; Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/metabolism ; Microbiota*

Source: PLoS pathogens [PLoS Pathog] 2024 Mar 08; Vol. 20 (3), pp. e1012012. Date of Electronic Publication: 2024 Mar 08 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Comparative evaluation of lateral flow assays to diagnose chronic Trypanosoma cruzi infection in Bolivia.

Authors : López R; Instituto Nacional de Laboratorios de Salud (INLASA), La Paz, Bolivia.; García A

Subjects: Trypanosoma cruzi* ; Chagas Disease*/Chagas Disease*/Chagas Disease*/parasitology; Humans

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Mar 04; Vol. 18 (3), pp. e0012016. Date of Electronic Publication: 2024 Mar 04 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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Trypanosoma cruzi infection induces DNA double-strand breaks and activates DNA damage response pathway in host epithelial cells.

Authors : Gonzáles-Córdova RA; Department of Cellular and Molecular Biology and Pathogenic Bioagents, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto, 14049-900, Brazil.; Dos Santos TR

Subjects: DNA Breaks, Double-Stranded* ; Chagas Disease*/Chagas Disease*/Chagas Disease*/genetics; Humans

Source: Scientific reports [Sci Rep] 2024 Mar 04; Vol. 14 (1), pp. 5225. Date of Electronic Publication: 2024 Mar 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Community-based actions in consulates: a new paradigm for opportunities for systematic integration in Chagas disease detection.

Authors : Gómez I Prat J; Department of Infectious Diseases, Public Health and Community Team (eSPiC), Drassanes-Vall d'Hebron International Health Unit (USIDVH), Vall d'Hebron University Hospital, Barcelona, Spain. .; International Health Program of the Catalan Institute of Health (PROSICS), Barcelona, Spain. .

Subjects: Strongyloidiasis* ; Chagas Disease*/Chagas Disease*/Chagas Disease*/diagnosis ; Chagas Disease*/Chagas Disease*/Chagas Disease*/epidemiology

Source: BMC infectious diseases [BMC Infect Dis] 2023 Dec 01; Vol. 23 (1), pp. 847. Date of Electronic Publication: 2023 Dec 01.Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334

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Quantitative PCR as a marker for preemptive therapy and its role in therapeutic control in Trypanosoma cruzi/HIV coinfection.

Authors : Freitas VLT; Departamento de Molestias Infecciosas e Parasitarias, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, São Paulo, Brazil.; Laboratorio de Investigacao Medica em Imunologia (LIM 48), Hospital das Clinicas, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil.

Subjects: Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/genetics ; Chagas Disease*/Chagas Disease*/Chagas Disease*/complications ; Chagas Disease*/Chagas Disease*/Chagas Disease*/drug therapy

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Feb 26; Vol. 18 (2), pp. e0011961. Date of Electronic Publication: 2024 Feb 26 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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Human Trypanosoma cruzi infection in the Argentinean Chaco: risk factors and identification of households with infected children for treatment.

Authors : Macchiaverna NP; Facultad de Ciencias Exactas y Naturales, Laboratorio de Eco-Epidemiología, Universidad de Buenos Aires, Ciudad Universitaria, Buenos Aires, Argentina. .; Instituto de Ecología, Genética y Evolución de Buenos Aires, Consejo Nacional de Investigaciones Científicas y Técnicas, Ciudad Universitaria, Buenos Aires, Argentina. .

Subjects: Chagas Disease*/Chagas Disease*/Chagas Disease*/epidemiology ; Trypanosoma cruzi*; Animals

Source: Parasites & vectors [Parasit Vectors] 2024 Jan 29; Vol. 17 (1), pp. 41. Date of Electronic Publication: 2024 Jan 29.Publisher: BioMed Central Country of Publication: England NLM ID: 101462774 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-3305

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Efficacy of short-course treatment for prevention of congenital transmission of Chagas disease: A retrospective cohort study.

Authors : Moscatelli G; Servicio de Parasitología y Chagas, Hospital de Niños 'Ricardo Gutiérrez', Buenos Aires, Argentina.; Instituto Multidisciplinario de Investigaciones en Patologías Pediatricas (IMIPP)- CONICET-GCBA, Buenos Aires, Argentina.

Subjects: Chagas Disease*/Chagas Disease*/Chagas Disease*/drug therapy ; Chagas Disease*/Chagas Disease*/Chagas Disease*/prevention & control ; Nitroimidazoles*/Nitroimidazoles*/Nitroimidazoles*/therapeutic use

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Jan 22; Vol. 18 (1), pp. e0011895. Date of Electronic Publication: 2024 Jan 22 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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Chagas cardiomyopathy in Boston, Massachusetts: Identifying disease and improving management after community and hospital-based screening.

Authors : Reifler KA; Section of Infectious Disease, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, United States of America.; Wheelock A

Subjects: Chagas Cardiomyopathy*/Chagas Cardiomyopathy*/Chagas Cardiomyopathy*/diagnosis ; Chagas Cardiomyopathy*/Chagas Cardiomyopathy*/Chagas Cardiomyopathy*/epidemiology ; Chagas Cardiomyopathy*/Chagas Cardiomyopathy*/Chagas Cardiomyopathy*/complications

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Jan 19; Vol. 18 (1), pp. e0011913. Date of Electronic Publication: 2024 Jan 19 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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Characterization of Novel Trypanosoma cruzi -Specific Antigen with Potential Use in the Diagnosis of Chagas Disease.

Authors : Ossowski MS; Instituto de Investigaciones en Ingeniería Genética y Biología Molecular 'Dr. Héctor N. Torres' (INGEBI-CONICET), Buenos Aires 1428, Argentina.; Gallardo JP

Subjects: Trypanosoma cruzi* ; Chagas Disease*/Chagas Disease*/Chagas Disease*/diagnosis ; Leishmania*

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 18; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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An α-Gal antigenic surrogate as a biomarker of treatment evaluation in Trypanosoma cruzi-infected children. A retrospective cohort study.

Authors : Abal M; Instituto de Investigaciones Biotecnológicas (IIBio), Universidad Nacional de San Martín (UNSAM), and Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.; Escuela de Bio y Nanotecnologías (EByN), UNSAM, Buenos Aires, Argentina.

Subjects: Trypanosoma cruzi* ; Chagas Disease*/Chagas Disease*/Chagas Disease*/diagnosis ; Chagas Disease*/Chagas Disease*/Chagas Disease*/drug therapy

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Jan 18; Vol. 18 (1), pp. e0011910. Date of Electronic Publication: 2024 Jan 18 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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Discovery of circulating miRNAs as biomarkers of chronic Chagas heart disease via a small RNA-Seq approach.

Authors : Villar SR; Instituto de Inmunología Clínica y Experimental de Rosario (IDICER-CONICET-UNR), Rosario, Argentina.; Herreros-Cabello A

Subjects: Circulating MicroRNA* ; MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism ; Heart Diseases*

Source: Scientific reports [Sci Rep] 2024 Jan 12; Vol. 14 (1), pp. 1187. Date of Electronic Publication: 2024 Jan 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Metacyclogenesis as the Starting Point of Chagas Disease.

Authors : Ferreira AZL; Pathogen-Host Interface Laboratory, Department of Cell Biology, University of Brasilia, Brasilia 70910-900, Brazil.; de Araújo CN

Subjects: Chagas Disease* ; Trypanosoma cruzi*; Humans

Source: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 21; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Parasite DNA and Markers of Decreased Immune Activation Associate Prospectively with Cardiac Functional Decline over 10 Years among Trypanosoma cruzi Seropositive Individuals in Brazil.

Authors : Sunderraj A; Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.; Cunha LM

Subjects: Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/genetics ; Parasites* ; Chagas Disease*

Source: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 19; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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